Endocrine / Hormonal
Abaloparatide
Abaloparatide is a synthetic peptide analog of PTHrP that functions as a selective agonist of the PTH1 receptor to stimulate bone formation.
Evidence: 0 articles
Goals: 0
Mechanism of Action
Abaloparatide acts as a selective agonist of the parathyroid hormone receptor type 1 (PTH1R). By binding to this receptor, it activates the cAMP signaling pathway, which promotes osteoblastic bone formation on trabecular and cortical bone surfaces with a reduced impact on bone resorption compared to traditional PTH analogs.
Evidence Level
Clinical Trial - Human
0 studies published
Pharmacology
Molecular Weight
3961 Da