Endocrine / Hormonal
Desmopressin
Desmopressin is a synthetic peptide analogue of the endogenous hormone vasopressin, primarily utilized for its antidiuretic and hemostatic properties.
Evidence: 0 articles
Goals: 0
Mechanism of Action
Desmopressin acts as a selective agonist for the vasopressin V2 receptors located in the renal collecting ducts. Activation of these receptors increases water permeability by promoting the translocation of aquaporin-2 water channels to the apical membrane, thereby enhancing water reabsorption and reducing urine production. Additionally, it stimulates the release of von Willebrand factor and factor VIII from endothelial cells, contributing to its hemostatic effects.
Evidence Level
Review
0 studies published
Pharmacology
Molecular Weight
1069.2 Da