Endocrine / Hormonal
Octreotide
Octreotide is a potent synthetic octapeptide analog of naturally occurring somatostatin with a longer half-life and enhanced inhibitory properties.
Evidence: 0 articles
Goals: 0
Mechanism of Action
Octreotide functions by binding to somatostatin receptors (SSTRs), particularly subtypes 2 and 5, which are coupled to inhibitory G proteins. This activation inhibits the release of various endocrine and exocrine hormones, including growth hormone (GH), glucagon, insulin, and vasoactive intestinal peptide (VIP), by modulating intracellular signaling pathways such as phospholipase C and calcium channel activity.
Evidence Level
Clinical Trial - Human
0 studies published
Pharmacology
Molecular Weight
1019.2 Da