Melanotan 2
Non-selective melanocortin receptor agonist studied for tanning and libido effects.
Mechanism of Action
Melanotan 2 (MT2) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone (α-MSH). It is a non-selective agonist of melanocortin receptors (MC1R, MC3R, MC4R, MC5R). Activation of MC1R stimulates melanogenesis (skin tanning). Activation of MC4R in the CNS is associated with appetite suppression and sexual arousal effects, similar to the mechanism of PT-141. MT2 is widely studied in animal models for its combined pigmentation and libido effects.
Evidence Chain
Melanotan 2
COMPOUND
1 Research Goal
• Sexual Health & Libido
Evidence Strength
1 article sourced
Knowledge Graph
(2 connections)Research Goals
(1)Related Compounds
Synergy & Compatibility
(5)Computational assessment of bio-regulatory compatibility with compounds sharing research goals. Scores reflect half-life alignment, receptor target overlap, and bioavailability data.
Highest Compatibility
Melanotan 2 + PT-141 (Bremelanotide)
Moderate Compatibility
Shared targets: mc1r, mc3r, mc4r…
Computational assessment based on available pharmacology data. Does not account for individual variability, dose-dependent effects, or unstudied interactions. For research use only.
Community Observations
(0)Qualitative, self-reported researcher observations. Distinct from peer-reviewed evidence — not medical advice.
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For research use only. Not medical advice.